Beilstein J. Org. Chem.2017,13, 1168–1173, doi:10.3762/bjoc.13.115
engineering and evolution of these proteins for biocatalyst application.
Keywords: alkaloid biogenesis; biosynthetic divergency; C–H activation; halogenase; non-hemeironenzyme; Introduction
Carbon–halogen (C–X) bonds are prevalent structural motifs in modern agrochemicals, pharmaceuticals and bioactive
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Graphical Abstract
Figure 1:
Comparative analysis of hapalindole-type alkaloids and their BGCs in two welwitindolinone producers...